发明名称 |
SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH |
摘要 |
The present invention relates to a compound of the formula I;;wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds. |
申请公布号 |
US2017001981(A1) |
申请公布日期 |
2017.01.05 |
申请号 |
US201615263041 |
申请日期 |
2016.09.12 |
申请人 |
PFIZER, INC. |
发明人 |
Luzzio Michael Joseph;Freeman-Cook Kevin Daniel;Bhattacharya Samit Kumar;Hayward Matthew Merrill;Hulford Catherine Angela;Autry Christopher Lowell;Zhao Xumiao;Xiao Jun;Nelson Kendra Louise |
分类号 |
C07D401/12 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
1. A method of making a compound of Formula (1), or a pharmaceutically acceptable salt thereof, the method comprising: reacting a compound of Formula (C3): with a compound of Formula (B5): thereby providing the compound of Formula (1), or a pharmaceutically acceptable salt thereof. |
地址 |
New York NY US |