发明名称 |
LIGAND-CYTOTOXICITY DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND USES THEREOF |
摘要 |
The present invention relates to a ligand-cytotoxic drug conjugate, preparation method and pharmaceutical use thereof. More specifically, the present invention provides a ligand-cytotoxic drug conjugate of general formula Pc-(X-Y-D) n , their preparation method and use of the ligand-cytotoxic drug conjugate and a pharmaceutical composition containing the same in the preparation of a medicament for the treatment of cancer via receptor modulation. |
申请公布号 |
EP3100731(A1) |
申请公布日期 |
2016.12.07 |
申请号 |
EP20150743477 |
申请日期 |
2015.01.22 |
申请人 |
Shanghai Hengrui Pharmaceutical Co., Ltd.;Jiangsu Hengrui Medicine Co., Ltd. |
发明人 |
WANG, Yali;ZHANG, Lianshan;LIANG, Jindong;LI, Ang;YANG, Fanglong |
分类号 |
A61K31/537;A61K35/00;A61K45/00;A61K47/48 |
主分类号 |
A61K31/537 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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