发明名称 |
BIPHASIC LIPID-VESICLE COMPOSITION AND METHOD FOR TREATING CERVICAL DYSPLASIA BY INTRAVAGINAL DELIVERY |
摘要 |
A biphasic lipid vesicle composition for treating cervical displasia by intravaginal delivery. The composition includes a suspension of lipid-bilayer vesicles having entrapped therein, an oil-in-water emulsion, human interferon alpha-2b and L-methionine, the composition having an interferon alpha-2b specific activity of between about 1-10 MIU (million international units) per gram composition, and between 0.01 to 0.5 weight percent L-methionine. In the treatment method, the composition is administered at a dose of between about 1-20 MIU interferon alpha-2b, and this dose is administered at least 3 days/week, for a period of at least 4 weeks. |
申请公布号 |
EP2134353(B1) |
申请公布日期 |
2016.11.16 |
申请号 |
EP20080733666 |
申请日期 |
2008.03.27 |
申请人 |
HELIX BIOPHARMA CORP. |
发明人 |
FOLDVARI, MARIANNA;KUMAR, PRAVEEN;DOCHERTY, JOHN, M. |
分类号 |
A61K38/21;A61K9/00;A61K9/06;A61K9/10;A61K9/107;A61K9/127;A61K31/198;A61K47/18 |
主分类号 |
A61K38/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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