发明名称 |
ASSESSMENT OF THE PI3K CELLULAR SIGNALING PATHWAY ACTIVITY USING MATHEMATICAL MODELLING OF TARGET GENE EXPRESSION |
摘要 |
The present invention relates to a method comprising inferring activity of a PI3K cellular signaling pathway in a tissue and/or cells and/or a body fluid of a medical subject based at least on expression levels of one or more target gene(s) of the PI3K cellular signaling pathway measured in an extracted sample of the tissue and/or the cells and/or the body fluid of the medical subject. The present invention further relates to an apparatus comprising a digital processor configured to perform such a method, a non-transitory storage medium storing instructions that are executable by a digital processing device to perform such a method, and a computer program comprising program code means for causing a digital processing device to perform such a method. |
申请公布号 |
EP3013986(B1) |
申请公布日期 |
2016.11.16 |
申请号 |
EP20140824498 |
申请日期 |
2014.12.30 |
申请人 |
KONINKLIJKE PHILIPS N.V. |
发明人 |
VAN OOIJEN, HENDRIK JAN;VERHAEGH, WILHELMUS FRANCISCUS JOHANNES;VAN DE STOLPE, ANJA |
分类号 |
C12Q1/68;G06F19/10 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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