METHODS OF T CELL EPITOPE PROFILING, MAKING T CELL COMPOSITIONS, AND TREATING DISEASES

摘要

Disclosed herein is a method of detecting antigen specific T cells in a sample isolated from a subject and mapping immunostimulatory epitopes of the antigen. Such methods may be used in methods of making antigen specific T cell compositions, e.g., for the treatment of diseases such as cancer, infectious diseases and autoimmune disorders.