发明名称 METHOD OF IMMOBILIZING A CELL ON A SUPPORT USING COMPOUNDS COMPRISING A POLYETHYLENE GLYCOL MOIETY
摘要 The present invention relates to a method of immobilizing a cell on a support, the method comprising a) providing a compound or salt thereof comprising, preferably consisting of, one or more hydrophobic domains attached to a hydrophilic domain, wherein the one or more hydrophobic domains are covalently bound to said hydrophilic domain, and wherein the one or more hydrophobic domains each comprise a linear lipid, a steroid or a hydrophobic vitamin, and wherein the hydrophilic domain comprises a polyethylene glycol (PEG) moiety, and wherein the compound comprises a linking group; b) contacting a cell with the compound under conditions allowing the interaction of the compound with the membrane of the cell, thereby immobilizing the linking group on the surface of the cell; and c) contacting the linking group immobilized on the cell with a support capable of binding the linking group, thereby immobilizing the cell on the support.
申请公布号 EP3084433(A1) 申请公布日期 2016.10.26
申请号 EP20140825324 申请日期 2014.12.19
申请人 ROCHE DIAGNOSTICS GMBH;F. HOFFMANN-LA ROCHE AG 发明人 JOSEL, HANS-PETER;HEINDL, DIETER;FROEHLICH, THOMAS;FROEHNER, STEFANIE
分类号 G01N33/50;C12N11/00;C12N11/06;G01N33/543 主分类号 G01N33/50
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