| 主权项 |
1. A method of treating diabetic nephropathy, comprising:
administering to a subject a therapeutically effective amount of a therapeutic agent selected from the group consisting of: an inhibitor of ErbB4, an inhibitor of Notch-1, miR-146a, a nucleic acid encoding miR-146a, a nucleic acid encoding pre-miR-146a, an miR-146a mimic, a pre-miR-146a mimic, an agent that increases the level of miR-146a, and a combination thereof; wherein said subject has been diagnosed with diabetes or diabetes susceptibility, and wherein said subject has a low miR-146a level in the glomerular tissue and/or podocytes in comparison to a suitable control. |
