发明名称 IMPROVED PROCESS FOR PRODUCING MAGNETIC MONODISPERSE POLYMER PARTICLES
摘要 Disclosed is a simplified process for producing magnetic polymer particles. The process comprises: (a) providing a composition having a liquid monomer which is radical polymerizable, a radical initiator soluble in the monomer, a steric stabilizer, and a ferrofluid comprising surfactant-coated colloidal magnetic particles in a carrier fluid which is miscible with the monomer; (b) preparing an emulsion from a polar solvent which is immiscible with the monomer, and the composition of step (a); (c) adding seed polymer particles to the emulsion, mixing to form a seeded emulsion, and incubating the seeded emulsion, thereby swelling the seed polymer particles; and (d) activating the radical initiator and polymerizing the monomer in the swollen seed polymer particles; thereby producing the magnetic polymer particles. The process forms monodisperse magnetic particles. The particles are characterized by a uniform distribution of magnetic material, and an absence of magnetite bleeding.
申请公布号 EP3078035(A1) 申请公布日期 2016.10.12
申请号 EP20140805947 申请日期 2014.12.03
申请人 F.HOFFMANN-LA ROCHE AG;ROCHE DIAGNOSTICS GMBH 发明人 SEIDEL, CHRISTOPH;BOLLE, JENS CHRISTIAN;RECKLIES, SANDRA
分类号 H01F1/00;C08F257/02 主分类号 H01F1/00
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