发明名称 |
TRIAZOLE ALCOHOL DERIVATIVE AND PREPARATION METHOD AND USE THEREOF |
摘要 |
The present invention relates to a triazole alcohol derivative and a preparation method and use thereof. The triazole alcohol derivative is a 2-(2,4-difluorophenyl )-3-(1-substituted-1H-1,2,3-triazol-4-yl)-1-(1H-1,2,4-triazol-1-yl)butyl-2-ol compound. The present invention also provides salts, pharmaceutical compositions, the preparation method and the use of the compound. The compound of the present invention has an antifungal activity, and has a low toxicity, a broad antibacterial spectrum, and the like, and can be used for preparing antifungal drugs. |
申请公布号 |
WO2016141747(A1) |
申请公布日期 |
2016.09.15 |
申请号 |
WO2015CN98002 |
申请日期 |
2015.12.21 |
申请人 |
SECOND MILITARY MEDICAL UNIVERSITY OF THE PEOPLE'S LIBERATION ARMY;YANTAI DONGCHENG PHARMACEUTICAL GROUP CO.,LTD |
发明人 |
ZHANG, Dazhi;JIANG, Yuanying;NITING, Junhong;CAI, Zhan;YOU, Shouyi;YANG, Zhenqiu;QI, Dongqi |
分类号 |
C07D249/08;A61K31/4196;A61K31/4439;A61K31/506;A61P31/10;C07D401/14;C07D403/14 |
主分类号 |
C07D249/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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