| 摘要 |
Provided are analgesic compounds of formula I and pharmaceutically acceptable salts thereof:wherein A isand R, R, R, R, R, R, R, R, R, Rand Rare disclosed herein and wherein one of A), B), and C) is present: A) Rand Rcombine to form -CH- or -(CH)-; B) Rand Rcombine to form a cyclopropyl group with the carbon to which they are attached; or C) Rand Rcombine to form -CH- or -(CH). Additionally, analgesic pharmaceutical formulations and methods of use employing the above compounds are provided. |
