发明名称 |
COMPOSITIONS OF KINASE INHIBITORS AND THEIR USE FOR TREATMENT OF CANCER AND OTHER DISEASES RELATED TO KINASES |
摘要 |
The present invention relates to novel thiazole-substituted indolin-2-ones as inhibitors of CSCPK and related kinases; to methods of inhibiting cancer stem cells by using a kinase inhibitor; to pharmaceutical compositions containing such compounds; and to methods of using such compounds in the treatment of protein kinase related disorder in a mammal; and to processes of making such compounds and intermediates thereof. |
申请公布号 |
EP2197878(B1) |
申请公布日期 |
2016.08.17 |
申请号 |
EP20080829600 |
申请日期 |
2008.09.05 |
申请人 |
BOSTON BIOMEDICAL, INC. |
发明人 |
LI, CHIANG, JIA;LIU, JI-FENG;LI, YOUZHI;LI, WEI;ROGOFF, HARRY |
分类号 |
C07D417/04;A61K31/427;A61K31/4439;A61K31/496;A61K45/06;C07D417/14 |
主分类号 |
C07D417/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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