发明名称 |
COMBINATION TUMOR TREATMENT WITH DRUG-LOADED, BISPECIFIC LIGAND-TARGETED MINICELLS AND INTERFERON-GAMMA |
摘要 |
Compositions and methods are provided for cancer treatments. The methodology entails, for instance, administering to a cancer patient a first composition comprising a plurality of bacterially derived intact minicells or intact killed bacterial cells, each of which encompasses an anti-neoplastic agent and carries a bispecific ligand on the surface, the ligand having specificity for a mammalian cell component, and a second composition comprising interferon-gamma (IFN-gamma) or an agent that increases the expression of IFN-gamma in the subject. The compositions include the first composition and the second composition as described, optionally with additional anti-neoplastic agents. |
申请公布号 |
EP3052122(A1) |
申请公布日期 |
2016.08.10 |
申请号 |
EP20140851383 |
申请日期 |
2014.10.03 |
申请人 |
ENGENEIC MOLECULAR DELIVERY PTY LTD. |
发明人 |
BRAHMBHATT, HIMANSHU;MACDIARMID, JENNIFER |
分类号 |
A61K38/21;A61K48/00;A61P35/00 |
主分类号 |
A61K38/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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