| 发明名称 |
INHIBITION OF A LNCRNA FOR TREATMENT OF MELANOMA |
| 摘要 |
This disclosure relates to the field of cancer, particularly the field of melanoma. It was found that a particular long non-coding RNA (lncRNA) is specifically up-regulated in melanoma (but not other tumor) cells as compared to melanocytes. Inhibition of this lncRNA in melanoma cells leads to induction of apoptosis and is a novel therapeutic strategy in the treatment of melanoma. |
| 申请公布号 |
EP3036326(A1) |
申请公布日期 |
2016.06.29 |
| 申请号 |
EP20140757881 |
申请日期 |
2014.08.20 |
| 申请人 |
VIB VZW;KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R&D;UNIVERSITEIT GENT |
发明人 |
MARINE, JEAN-CHRISTOPHE;LEUCCI, ELEONORA;VANDESOMPELE, JOKE;MESTDAGH, PIETER |
| 分类号 |
C12N15/113;A61K31/7105;A61K31/713;A61P35/00;C12Q1/68;G01N33/574 |
主分类号 |
C12N15/113 |
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