发明名称 Methods and Compositions for Increasing the Efficacy of Doxorubicin Treatment in the Treatmentof Prostate Related Disorders using miR-106b-25 Cluster
摘要 Methods and compositions for the treatment of prostate associated disorders are disclosed.
申请公布号 US2016177316(A1) 申请公布日期 2016.06.23
申请号 US201615062414 申请日期 2016.03.07
申请人 The Ohio State University Research Foundation ;The Government of the United States of America, as represented by the Secretary of the Department of 发明人 Croce Carlo M.;Ambs Stefan
分类号 C12N15/113 主分类号 C12N15/113
代理机构 代理人
主权项 1. A method for increasing the efficacy of a doxorubicin treatment in a subject receiving such treatment, comprising administering an effective amount of a miR gene product from the miR-106b-25 cluster in an amount sufficient to decrease inhibition of caspase-3/caspase-7 activation in anticancer drug-treated cells.
地址 Columbus OH US