Topical formulations having enhanced bioavailability

摘要

TOPICAL FORMULATIONS HAVING ENHANCED BIOAVAILABILITY Abstract The present disclosure provides compositions suitable for delivering lipophilic bioactive agents. The compositions may be utilized to treat numerous diseases and conditions that would benefit from the application of a lipophilic bioactive agent. Figure 1: Mean * SD CoQjo Epidermal Concentration vs Dose (Male Pig): (n=6/skin section) 700- Lof Side -q- R1 ide (14)sy DOdng) - 200 Dose (mg) Figure 2: Mean * SD CoQjo Epidermal Concentration vs Dose (Female Pig): (n=6/skin section) - L-t~o SIM (7-Day Odang) 0 1 2 3 4 5 Dose (mg)