发明名称 |
CELLULAR-BASED METHOD FOR DETERMINING THE POTENCY OF DEFIBROTIDE |
摘要 |
The present invention relates to cell-based methods for determining the biological activity of defibrotide. In particular, the invention provides a method for assessing the potency of defibrotide by assessing the viability of mammalian cells in the presence of at least one cytotoxic agent and one or more concentrations of defibrotide. Such methods are particularly useful for standardizing pharmaceutical compositions comprising defibrotide. |
申请公布号 |
WO2016083297(A1) |
申请公布日期 |
2016.06.02 |
申请号 |
WO2015EP77355 |
申请日期 |
2015.11.23 |
申请人 |
GENTIUM S.P.A. |
发明人 |
IGNONI, TERENZIO;KUMAR, VIJAY;VERGA, CLAUDIO |
分类号 |
G01N33/86 |
主分类号 |
G01N33/86 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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