| 发明名称 |
COMPOSITIONS AND METHODS FOR TREATING SCHIZOPHRENIA |
| 摘要 |
The disclosure provides a novel polymorph of Compound (I):;;2-((1-(2-(4-Fluorophenyl)-2-oxoethyl)piperidin-4-yl)methyl)isoindolin-1-one monohydrochloride dihydrate, i.e., Form (A) of Compound (I).HCl.2H2O. Pharmaceutical compositions comprising Form (A) of Compound (I).HCl.2H2O and related methods of treatment are also disclosed. |
| 申请公布号 |
US2016152597(A1) |
申请公布日期 |
2016.06.02 |
| 申请号 |
US201514954264 |
申请日期 |
2015.11.30 |
| 申请人 |
MINERVA NEUROSCIENCES, INC. |
发明人 |
LUTHRINGER REMY;OKUYAMA MASAHIRO |
| 分类号 |
C07D401/06 |
主分类号 |
C07D401/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A crystalline form of Compound (I);comprising a polymorph form (A) of Compound (I).HCl.2H2O, and wherein the form (A) has a X-ray powder diffraction pattern with at least one major peak substantially similar to at least one major peak shown in FIG. 11. |
| 地址 |
Waltham MA US |
