发明名称 HISTONE DEMETHYLASE INHIBITORS
摘要 The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted amidopyridine or amidopyridazine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
申请公布号 EP2935217(A4) 申请公布日期 2016.06.01
申请号 EP20130865712 申请日期 2013.12.23
申请人 QUANTICEL PHARMACEUTICALS INC 发明人 CHEN, YOUNG, K.;KANOUNI, TOUFIKE;NIE, ZHE;STAFFORD, JEFFREY, ALAN;VEAL, JAMES, MARVIN;WALLACE, MICHAEL, BRENNAN
分类号 C07D213/74;A61K31/44;A61K31/50;A61K31/501;A61P35/00;C07D213/79;C07D213/81;C07D237/24;C07D401/04;C07D401/12;C07D405/12;C07D405/14;C07D409/12;C07D409/14 主分类号 C07D213/74
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