| 发明名称 |
N,6-BIS(ARYL OR HETEROARYL)-1,3,5-TRIAZINE-2,4-DIAMINE COMPOUNDS AS IDH2 MUTANTS INHIBITORS FOR THE TREATMENT OF CANCER |
| 摘要 |
Provided are compounds of formula (I), Wherein: ring A and ring B are each independently an optionally substituted 5-6 membered monocyclic aryl or heteroaryl. The compounds are inhibitors of isocitrate dehydrogenase 2 (IDH2) mutants useful for treating cancer. |
| 申请公布号 |
EP3019490(A1) |
申请公布日期 |
2016.05.18 |
| 申请号 |
EP20140745309 |
申请日期 |
2014.07.10 |
| 申请人 |
AGIOS PHARMACEUTICALS, INC. |
发明人 |
TRAVINS, JEREMY;UTLEY, LUKE |
| 分类号 |
C07D401/14;A61K31/53;A61P35/00;C07D251/18;C07D401/04;C07D401/12;C07D403/04;C07D403/12;C07D413/12;C07D417/12;C07D417/14 |
主分类号 |
C07D401/14 |
| 代理机构 |
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