Plication Lock Delivery System and Method of Use Thereof

摘要

A plication lock delivery system that enables a suture lock assembly to be delivered percutaneouly. The plication lock delivery system comprises a lock assembly that secures sutures in place, a control assembly that allows a clinician to engage a suture to a suture lock assembly, apply tension to the sutures to cause tissue plication, and deploy the lock assembly, and a catheter assembly. This plication lock delivery system can be used to repair mitral regurgitation percutaneouly or in an open-heart surgery.

主权项

1. A plication lock delivery system for creating a tissue plication comprising:
a lock assembly comprising a lock body and a lock pin, wherein the lock body has a central lumen configured to retain the lock pin and to have a first and a second sutures disposed within the central lumen; a catheter assembly comprising an outer sheath and an inner catheter, wherein the inner catheter has a distal end, a proximal end, and a central lumen, wherein the distal end of the inner catheter is configured to detachably connect to the lock body, wherein the central lumen is configured to have the first and the second sutures disposed within, wherein the outer sheath has a distal end and a proximal end, wherein the distal end is configured to contact the lock pin and cause movement thereof; and a control assembly comprising a first suture tension mechanism configured to apply tension to a first suture, a second suture tension mechanism configured to apply tension to a second suture, and a lock deploy-and-release mechanism configured to secure the first and the second sutures to the lock assembly and to release the lock assembly from the catheter assembly at a target site; wherein the control assembly is operatively coupled to the proximal ends of the outer sheath and inner catheter.