发明名称 |
Method for inducing erythropoietin-producing cell |
摘要 |
An object of the present invention is to provide a method for inducing the differentiation of erythropoietin-producing cells from human pluripotent stem cells. The above object is achieved by providing a method for inducing the differentiation of erythropoietin-producing cells from human pluripotent stem cells using a medium containing a specific growth factor and a specific compound. |
申请公布号 |
US9334475(B2) |
申请公布日期 |
2016.05.10 |
申请号 |
US201314390853 |
申请日期 |
2013.04.04 |
申请人 |
KYOTO UNIVERSITY |
发明人 |
Osafune Kenji;Hitomi Hirofumi |
分类号 |
C12N5/00;C12N5/071 |
主分类号 |
C12N5/00 |
代理机构 |
Oblon, McClelland, Maier & Neustadt, L.L.P. |
代理人 |
Oblon, McClelland, Maier & Neustadt, L.L.P. |
主权项 |
1. A method for producing erythropoietin-producing cells from human pluripotent stem cells, comprising the steps of:
(i) culturing human pluripotent stem cells in a first medium comprising Activin and a GSK-3β inhibitor; and then (ii) culturing the human pluripotent stem cells in a second medium comprising an IGF family gene product. |
地址 |
Kyoto-shi JP |