发明名称 Method for inducing erythropoietin-producing cell
摘要 An object of the present invention is to provide a method for inducing the differentiation of erythropoietin-producing cells from human pluripotent stem cells. The above object is achieved by providing a method for inducing the differentiation of erythropoietin-producing cells from human pluripotent stem cells using a medium containing a specific growth factor and a specific compound.
申请公布号 US9334475(B2) 申请公布日期 2016.05.10
申请号 US201314390853 申请日期 2013.04.04
申请人 KYOTO UNIVERSITY 发明人 Osafune Kenji;Hitomi Hirofumi
分类号 C12N5/00;C12N5/071 主分类号 C12N5/00
代理机构 Oblon, McClelland, Maier & Neustadt, L.L.P. 代理人 Oblon, McClelland, Maier & Neustadt, L.L.P.
主权项 1. A method for producing erythropoietin-producing cells from human pluripotent stem cells, comprising the steps of: (i) culturing human pluripotent stem cells in a first medium comprising Activin and a GSK-3β inhibitor; and then (ii) culturing the human pluripotent stem cells in a second medium comprising an IGF family gene product.
地址 Kyoto-shi JP