| 发明名称 |
Synthetic rigidin analogues as anticancer agents, salts, solvates and prodrugs thereof, and method of producing same |
| 摘要 |
A compound having the Formula as follows:;
wherein R, R1 and R2 are selected from hydrogen, aryl, fused aryl, heteroaryl, saturated carbocylclic, partially saturated carbocyclic, saturated heterocyclic, partially saturated heterocyclic, C1-10 alkyl, haloalkyl, alkenyl, alkynyl, arylalkyl, arylalkenyl, arylalkynyl, heteroarylalkyl, heteroarylalkenyl, alkenylalkyl, alkynylalkyl, carbocycloalkyl, heterocycloalkyl, hydroxyalkyl, aminoalkyl, carboxyalkyl, nitroalkyl, cyanoalkyl, acetamidoalkyl, and acyloxyalkyl. A process for the preparation thereof is also provided. |
| 申请公布号 |
US9334280(B2) |
申请公布日期 |
2016.05.10 |
| 申请号 |
US201414584929 |
申请日期 |
2014.12.29 |
| 申请人 |
New Mexico Tech Research Foundation |
发明人 |
Magedov Igor V.;Rogelj Snezna;Frolova Liliya V;Kornienko Alexander Vladimir |
| 分类号 |
A01N43/90;A61K31/519;C07D487/00;C07D487/04 |
主分类号 |
A01N43/90 |
| 代理机构 |
|
代理人 |
Stachniak Jennifer S. |
| 主权项 |
1. A compound having the formula as follows: wherein R, R1 and R2 are selected from hydrogen, aryl, fused aryl, heteroaryl, saturated carbocylclic, partially saturated carbocyclic, saturated heterocyclic, partially saturated heterocyclic, C1-10 alkyl, haloalkyl, alkenyl, alkynyl, arylalkyl, arylalkenyl, arylalkynyl, heteroarylalkyl, heteroarylalkenyl, alkenylalkyl, alkynylalkyl, carbocycloalkyl, heterocycloalkyl, hydroxyalkyl, aminoalkyl, carboxyalkyl, nitroalkyl, cyanoalkyl, acetamidoalkyl, and acyloxyalkyl. |
| 地址 |
Socorro NM US |
