| 发明名称 |
PROCESSES FOR THE PREPARATION OF 6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXAMIDE AND OF ITS PRECURSORS |
| 摘要 |
The invention relates to a novel process for the preparation of rac-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide (I) in pharmaceutically acceptable polymorphic form, through the conversion of a 3-bromo-2-oxo-cyclohexanecarboxylic acid alkyl ester into 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid alkyl ester, which in turn is processed to yield the final product. |
| 申请公布号 |
EP2768807(B1) |
申请公布日期 |
2016.05.04 |
| 申请号 |
EP20120783161 |
申请日期 |
2012.10.19 |
| 申请人 |
SIENA BIOTECH S.P.A. |
发明人 |
DIODATO, ENRICA;MARCUCCI, KATIA;THOMAS, RUSSELL;WIEDENAU, PAUL;RETTIG, MARTIN;ROBERTS, HUW |
| 分类号 |
C07D209/88 |
主分类号 |
C07D209/88 |
| 代理机构 |
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