Method and system for preparation of liquid mixtures

摘要

A method for preparing a liquid flow having pre-defined characteristics by mixing liquid flows of at least two different component stock solutions with each other comprises the steps of determining a selected property value for one or more of the stock solutions by sensing, in a flow of each stock solution separately, at least one characteristic related to the property value for the stock solution, and based on the determined property value or values, mixing the stock solution flows in mixing ratios giving the desired mixed liquid flow. A system for carrying out the method comprises sensor means and a control unit, wherein the control unit is arranged to evaluate the characteristics sensed by the sensor means and provide relative ratios of stock solutions required to obtain a mixed liquid flow having the pre-defined characteristics.

主权项

1. A method of preparing a buffer solution using a plurality of stock solutions, the buffer solution having predetermined characteristics, the method executed by a flow control system, and the method comprising:
combining the plurality of stock solutions to obtain the buffer solution, the combining including: sensing a current value of a property of a first stock solution, a current value of a property of a second stock solution, and a current value of a property of a third stock solution; determining whether the sensed current value for the first stock solution is within a predetermined range; adjusting the current value for the first stock solution to within the predetermined range, when the sensed current value is not in the predetermined range, by flow-feedback of the first stock solution and by continuously sensing the current value for the first stock solution and determining whether the sensed current value for the first stock solution is within the predetermined range; calculating a relative proportion for each one of the second stock solution and the third stock solution based on (i) the sensed current value of the property for the second stock solution, (ii) the sensed current value of the property for the third stock solution, and (iii) the predetermined characteristics of the buffer; adjusting, in response to the calculating and according to the respective relative proportions, flow rates of the second stock solution and the third stock solution; and mixing the first stock solution, the second stock solution, and the third stock solution to obtain the buffer solution.