| 发明名称 |
ALUMINUM COMPOUNDS FOR USE IN THERAPEUTICS AND VACCINES |
| 摘要 |
The invention relates to means and methods for preparing aqueous composition comprising aluminium and a protein said composition comprising less than 700 ppm heavy metal on the basis of weight with respect to the aluminium content. The invention further relates to aqueous compositions comprising a protein and an aluminium-salt, said composition comprising less than 350 ppb heavy metal based on the weight of the aqueous composition. |
| 申请公布号 |
US2016114033(A1) |
申请公布日期 |
2016.04.28 |
| 申请号 |
US201514873344 |
申请日期 |
2015.10.02 |
| 申请人 |
Valneva Austria GmbH |
发明人 |
Schlegl Robert;Möhlen Michael;Wruss Jürgen;Weber Michael |
| 分类号 |
A61K39/39;C12N7/00;A61K39/12 |
主分类号 |
A61K39/39 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for preparing an aqueous composition comprising aluminium, a reactive compound and a protein antigen, said method comprising
selecting an aluminium-salt that is able to provide an aqueous composition having less than 1.25 ppb Cu based on the weight of the aqueous composition and combining said aluminium salt, said reactive compound, said protein antigen and water to produce said aqueous composition. |
| 地址 |
Vienna AT |
