发明名称 |
NEW SCAFFOLDS AND MULTIFUNCTIONAL INTERMEDIATES FOR IMAGING PSMA AND CANCER THERAPY |
摘要 |
Carbamate and beta-amino acid urea-based scaffolds that have high binding affinity to PSMA are disclosed. These scaffolds can be radiolabeled and used for imaging cells and tumors that express PSMA or for cancer radiotherapy. These compounds also can comprise a fluorescent dye and be used for imaging cells and tumors that express PSMA or for photodynamic therapy. |
申请公布号 |
WO2016065142(A2) |
申请公布日期 |
2016.04.28 |
申请号 |
WO2015US56909 |
申请日期 |
2015.10.22 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
POMPER, MARTIN G.;MEASE, RONNIE C.;RAY, SANGEETA;CHEN, YING;YANG, XING |
分类号 |
C07D249/04;A61K47/48;A61K49/06;A61K49/10;A61K51/04;A61P35/00 |
主分类号 |
C07D249/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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