发明名称 |
CANCER BIOMARKERS AND USES THEREOF |
摘要 |
The invention relates the use of Human Epidermal Growth Factor Receptor 2 (HER2) gene copy number and HER2 mRNA levels as biomarkers to identify cancers which will respond to treatment with a specific binding member comprising a HER2 antigen binding site engineered into a structural loop region of a constant domain, e.g. CH3 domain, of the specific binding member, and specific binding members which compete with such a binding member for binding to HER2. |
申请公布号 |
SG11201602605T(A) |
申请公布日期 |
2016.04.28 |
申请号 |
SGT11201602605 |
申请日期 |
2014.10.03 |
申请人 |
F-STAR BIOTECHNOLOGY LTD;F-STAR BIOTECHNOLOGISCHE FORSCHUNGS- UND ENTWICKLUNGSGES.M.B.H. |
发明人 |
LEUNG, KINMEI;SUN, HAIJUN;BATEY, SARAH;ROWLAND, ROBERT |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|