A medication management system according to some embodiment may include a box with multiple sections and medication packaging strips. At least two of the medication packaging strips may include medication dose envelopes serially connected together. At least two of the multiple sections in the box may include a dispensing opening allowing the medication packaging strips to be dispensed serially through the dispensing openings. The medication management system may include a tactile marker between medication dose envelopes. In some embodiments the tactile marker may include a notch in the medication packaging strip. The tactile marker may include a raised feature in the medication packaging strip. The tactile marker may be on an empty medication dose envelope positioned between and connecting two filled medication dose envelopes.
