marcador de diagnostio, uso de polipdeos agente de contraste uso de anticorpos, metodo de diagnostico de cancer colorretal ccr, metodo de diagnostico de cce metodo de aquisição de dados de uso de diagnostico de polipeptideo

摘要

Protein-based methods and compositions for the diagnosis of colorectal adenocarcinoma are disclosed. A method for indentifying cell-surface proteins, which are transmembrane proteins or proteins with a signal peptide and which are over-expressed in colorectal cancer (CRC) is disclosed. Biomarkers found with this method, diagnostic methods using them and contrast agents directed to them for use in magnetic resonance imaging (MRI) and/or magnetic photon imaging (MPI) are disclosed.
The methods and biomarkers allow for differentiating progressive (high-risk) CRC (adenocarcinomas) from non-progressive (low-risk) colorectal adenomas.