| 摘要 |
A column oven that may enable a heat block to provide the best temperature distribution, and increase temperature evenness of a column is provided. In a column oven 400 that heats or cools a heat block 10 contacting a column 40 and adjusts temperature of the column 40 through heat transmission from the heat block 10, a plurality of temperature adjustment bodies 21 and 22 is separately disposed along the longitudinal direction of the heat block 10, and heats or cools the heat block 10, a plurality of temperature sensors 31 and 32 measuring the temperatures of the heat block 10 adjacent to the temperature adjustment bodies 21 and 22 is also disposed, and the corresponding temperature adjustment bodies 21 and 22 are controlled independently according to the temperatures measured by the temperature sensors 31 and 32. |
| 主权项 |
1. A column oven, for heating or cooling one heat block contacting a column, and adjusting a temperature of the column through heat transmission from the heat block, the one heat block having a longitudinal direction of from an influx of the column to an outflux of the column, and the column oven comprising:
a) a plurality of temperature adjustment bodies, separately disposed along the longitudinal direction of the heat block, and heating or cooling the heat block; b) a plurality of temperature sensors, measuring temperatures of the heat block adjacent to the temperature adjustment bodies; c) a control unit, controlling the corresponding temperature adjustment bodies independently according to the temperatures of the heat block measured by the temperature sensors; and d) a temperature determination unit, respectively determining setting temperatures of temperature adjustment bodies according to an analysis condition that at least comprises a temperature of the column oven and a flow of a mobile phase applied in an analysis, wherein the control unit controls the temperature adjustment bodies in a manner of enabling the temperatures measured by the temperature sensors to reach the setting temperatures of the temperature adjustment bodies, the temperature determination unit determining the setting temperatures of the plurality of temperature adjustment bodies comprises: when the heat block is heated through the temperature adjustment bodies, the setting temperature of the temperature adjustment body disposed nearer to the influx of the column becomes higher, and the temperature determination unit derives a critical value of a setting temperature difference of the temperature adjustment bodies according to the analysis condition, and determines the setting temperatures of the temperature adjustment bodies in a manner such that the setting temperature difference of the temperature adjustment bodies is smaller than the critical value. |
