| 主权项 |
1. A compound of following general formula (I):wherein:
a) R12 represents H, and
R1 and R2 each independently are:
a halogen, straight-chain or branched C1 to C8 alkyl, C2-C8 alkene, straight-chain or branched C1 to C8 alkoxy, C3-C6 cycloalkyl, C5-C6 bicycloalkyl, a polyether chain, C1-C5 perfluoroalkyl, C1-C8 acyl, OH, SH, a primary, secondary or tertiary amine, CN, CO2H, CO2R′ where R′ is a straight-chain or branched C1-C8 alkyl or C3-C6 cycloalkyl; orR1 and R2 together form a C5 ring;R3, R4 and R5 each independently represent:
a hydrogen, a halogen, straight-chain or branched C1 to C8 alkyl, C2-C8 alkene, straight-chain or branched C1 to C8 alkoxy, C3-C6 cycloalkyl, C5-C6 bicycloalkyl, a polyether chain, a C1-C5 perfluoroalkyl, C1-C8 acyl, OH, SH, a primary, secondary or tertiary amine, CN, CO2H, CO2R′ where R′ is a straight-chain or branched C1-C8 alkyl, or a C3-C6 cycloalkyl;R6, R7, R9 and R11 represent hydrogens; andR8 and R10 are selected from the group consisting of a hydrogen and straight-chain or branched C1 to C5 alkyl, at least one of the two being a straight-chain or branched C1 to C5 alkyl; or b) R12 represents CH(R13)(CH2) and forms a C5 ring with R5, R13 representing H or CH3,
R1, R2, R3 and R4 are selected from the group consisting of a hydrogen, a halogen, straight-chain or branched C1 to C8 alkyl, C2-C8 alkene, straight-chain or branched C1 to C8 alkoxy, C3-C6 cycloalkyl, C5-C6 bicycloalkyl, a polyether chain, a C1-C5 perfluoroalkyl, C1-C8 acyl, —OH, —SH, a primary, secondary or tertiary amine, —CH, —CO2H, —CO2R′ where R′ is a straight-chain or branched C1-C8 alkyl, and a C3-C6 cycloalkyl;R6, R7, R9 and R11 represent hydrogens; andR8 and R10 are selected from the group consisting of a hydrogen and straight-chain or branched C1 to C5 alkyl, at least one of the two being a straight-chain or branched C1 to C5 alkyl,provided that at least one substituent selected from R1 and R13 is not a hydrogen; and pharmacologically acceptable salts thereof. |
