| 发明名称 |
Pharmaceutical compositions containing botulinum toxin |
| 摘要 |
This invention relates to the use of a composition comprising a polysaccharide and a botulinum toxin for reducing a skin wrinkle. In some embodiments, the polysaccharide comprises disaccharides. In some embodiments, the average molecular weight of a disaccharide unit of the polysaccharide is between about 345 D and about 1,000 D. |
| 申请公布号 |
US9302008(B2) |
申请公布日期 |
2016.04.05 |
| 申请号 |
US200711932878 |
申请日期 |
2007.10.31 |
| 申请人 |
Allergan, Inc. |
发明人 |
Hunt Terrence J. |
| 分类号 |
A61K39/08;A61K38/48;A61K9/00;A61K9/19;A61K8/73;A61K47/36;A61K47/22;A61K8/02;A61K8/44;A61K8/64;A61K8/65;A61K8/99;A61K31/715;A61K38/39;A61K47/18;A61K47/42;A61Q19/08;A61K38/16;B65D85/00;A61K8/66;C07K14/33 |
主分类号 |
A61K39/08 |
| 代理机构 |
|
代理人 |
Phan Brigitte C.;Chan Ted A. |
| 主权项 |
1. A solid pharmaceutical composition comprising a starch and a botulinum toxin type A, wherein the botulinum toxin type A is not stabilized by a protein excipient and wherein the botulinum toxin type A is mixed with a solution containing the starch to form a mixture, and wherein the mixture is lyophilized or vacuum-dried to form the solid pharmaceutical composition. |
| 地址 |
Irvine CA US |
