| 摘要 |
PROBLEM TO BE SOLVED: To provide drug compositions and methods for treating diseases with low bone density, promoting increase in bone growth or mineralization, and increasing bone density and bone strength.SOLUTION: The invention provides molecules having activin antagonist activity or ActRIIa antagonist activity ("activin antagonists" and "ActRIIa antagonists") acting as an inhibitor of activin-ActRIIa signaling in vivo, and administration of the antagonist compositions.SELECTED DRAWING: Figure 6 |
