TEST STRIPS FOR DETERMINING COAGULATION FACTOR ACTIVITIES

摘要

Test strips for determining the activity of a coagulation factor in a blood sample are provided. The strip comprises a support, a sample inlet port for deposition of a blood sample, and a reaction area comprising a blood coagulation reagent. The sample inlet port is connected to the reaction area, and the coagulation reagent comprises blood plasma deficient in the coagulation factor for which activity is to be measured, an ionic citrate source an ionic calcium source, and either one or more coagulation contact phase activator reagents and phospholipids or a mixture of tissue factor and phospholipids. The disclosure further relates to in vitro methods for measuring an activity of a coagulation factor.

主权项

1. A test strip for determining the activity of a coagulation factor of the intrinsic or extrinsic pathway in a blood sample, said strip comprising:
a support disposed on which are: a sample inlet port for deposition of a blood sample, and, a reaction area comprising a blood coagulation reagent, wherein the sample inlet port is connected to the reaction area, and wherein the coagulation reagent comprises the following ingredients:
plasma deficient in the coagulation factor for which activity is to be measured,an ionic citrate source,an ionic calcium source, and either
one or more coagulation contact phase activator reagents and phospholipids ora mixture of tissue factor and phospholipids.