发明名称 |
COMPOSITION FOR PREVENTING OR TREATING PERIPHERAL VASCULAR DISEASE USING HEPATOCYTE GROWTH FACTOR AND STROMAL CELL DERIVED FACTOR 1Α |
摘要 |
The present invention relates to a pharmaceutical composition for preventing or treating peripheral vascular disease, the composition comprising, as an active ingredient: (a) hepatocyte growth factor (HGF) or an isoform thereof, and stromal cell derived factor 1α (SDF-1α); or (b) a polynucleotide encoding the HGF and a polynucleotide encoding the SDF-1α. The peripheral vascular disease (for example, ischemic limb disease) can be more effectively prevented or treated through the significant promotion of vascular endothelial cell migration and angiogenesis in the case of singly using the composition of the present invention than in the case of using HGF, an isoform thereof, SDF-1α or a polynucleotide codes a protein thereof. |
申请公布号 |
WO2016048105(A1) |
申请公布日期 |
2016.03.31 |
申请号 |
WO2015KR10240 |
申请日期 |
2015.09.25 |
申请人 |
VIROMED CO., LTD. |
发明人 |
JEONG, JAE-GYUN;LEE, JUNG HUN;LEE, NAYEON |
分类号 |
A61K48/00;A61K38/18;A61P9/00;A61P9/10 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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