Provided herein is a bone repair composition that is composed of periosteum containing an angiogenic growth factor(s), cancellous bone chips containing viable osteogenic cells, and, optionally, demineralized bone matrix (DBM) chips. Also provided herein are articles of manufacture and use of the compositions and methods of use of the compositions to treat bone defects.
申请公布号
WO2016044030(A1)
申请公布日期
2016.03.24
申请号
WO2015US49248
申请日期
2015.09.09
申请人
OSIRIS THERAPEUTICS, INC.
发明人
UVEGES, THOMAS, E.;KUANG, JIN-QIANG;DANILKOVITCH, ALLA;SINCLAIR, S., MICHAEL;GERAGHTY, SANDRA, D.