SUBSTITUTED PHENYLAZOLE DERIVATIVE

摘要

Compounds are provided having an excellent hypoglycemic effect and β cell- or pancreas-protecting effects, or pharmaceutically acceptable salts thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause hyperglycemia due to abnormal glucose metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.;

主权项

1. A method of treating obesity, comprising administering to a mammal a compound of formula (VII):or a pharmaceutically acceptable salt thereof, wherein
X is CH or N, R1 is —C(═O)—NH—R5 or —NH—C(═O)—NH—R5, R3 is —CH3, and R5 is —H, or a C1-C6 alkyl group or a C3-C6 cycloalkyl group, each of which may be independently substituted with 1 to 3 —OH.