发明名称 |
METHOD FOR PREPARING ROSUVASTATIN CALCIUM INTERMEDIATE |
摘要 |
Disclosed is a method for preparing rosuvastatin calcium intermediate of formula I, which comprises hydrolyzing an ester compound of formula II (R is C1-C5 alkyl) in the presence of a metal compound to obtain a carboxylic acid compound of formula III, and then reducing the carboxylic acid compound under a specific reduction condition to obtain rosuvastatin calcium intermediate of formula I. |
申请公布号 |
EP2602250(B1) |
申请公布日期 |
2016.03.23 |
申请号 |
EP20110814062 |
申请日期 |
2011.06.15 |
申请人 |
PORTON FINE CHEMICALS LTD |
发明人 |
LIN, WENQING;ZHENG, HONGJIE;YANG, PENG |
分类号 |
C07D239/42 |
主分类号 |
C07D239/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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