发明名称 P2X7 MODULATING N-ACYL-TRIAZOLOPYRAZINES
摘要 The present invention is directed to compounds of Formula (I), which includes enantiomer and diasteromers thereof: These compounds are suitable for use in the treatment of diseases associated with P2X7 receptor activity such as diseases of the autoimmune and inflammatory system, diseases of the nervous and neuro-immune system, diseases involved with neuroinflammation of the Central Nervous System (CNS) or diseases of the cardiovascular, metabolic, gastrointestinal and urogenital systems.
申请公布号 WO2016039983(A1) 申请公布日期 2016.03.17
申请号 WO2015US46852 申请日期 2015.08.26
申请人 JANSSEN PHARMACEUTICA NV 发明人 ANDRES GIL, JOSE, IGNACIO;LETAVIC, MICHAEL, A.;RECH, JASON, C.;RUDOLPH, DALE, A.;SOYODE-JOHNSON, AKINOLA;CHROVIAN, CHRISTA, C.
分类号 C07D487/04;A61K31/4985;A61P29/00 主分类号 C07D487/04
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