发明名称 HUMAN ANTI-IL-6 ANTIBODIES WITH EXTENDED IN VIVO HALF-LIFE AND THEIR USE IN TREATMENT OF ONCOLOGY, AUTOIMMUNE DISEASES AND INFLAMMATORY DISEASES.
摘要 The present invention provides human anti-IL-6 antibodies with extended in vivo half-life. The invention further relates to pharmaceutical compositions, therapeutic compositions, and methods using therapeutic antibodies that bind to IL-6 and that has an extended in vivo half-life for the treatment and prevention of IL-6 mediated diseases and disorders, such as, but not limited to, inflammatory diseases and disorders, autoimmune diseases and disorders and tumors.
申请公布号 MX337590(B) 申请公布日期 2016.03.11
申请号 MX20110007832 申请日期 2010.01.29
申请人 MEDIMMUNE, LLC. 发明人 MICHAEL BOWEN.*;BAHIJA JALLAL;PETER KIENER;HERREN WU;WILLIAM DALL'ACQUA;ANTHONY COYLE
分类号 A61K39/395;C07K16/24 主分类号 A61K39/395
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