发明名称 |
PROCESS OF MAKING HYDROXYLATED CYCLOPENTAPYRIMIDINE COMPOUNDS AND SALTS THEREOF |
摘要 |
The invention provides new processes for making and purifying salts of hydroxylated cyclopentapyrimidine compounds, which are useful as AKT inhibitors used in the treatment of diseases such as cancer, including the monohydrochloride salt of (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one. |
申请公布号 |
HK1208500(A1) |
申请公布日期 |
2016.03.04 |
申请号 |
HK20150109047 |
申请日期 |
2015.09.16 |
申请人 |
GENENTECH INC. |
发明人 |
BABU, SRINIVASAN;GOSSELIN, FRANCIS;RAN, YINGQING;REMARCHUK, TRAVIS;SAVAGE, SCOTT J.;STULTS, JEFFREY;YAJIMA, HERBERT |
分类号 |
C12P;C07D |
主分类号 |
C12P |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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