| 发明名称 |
STABLE RECOMBINANT ADENOSINE DEAMINASE |
| 摘要 |
A mutein recombinant adenosine deaminase having any oxidizable cysteine residue replaced by a non-oxidizable amino acid residue is disclosed. Stabilized recombinant adenosine deaminase, polymer conjugates and methods of treatment using the same are also disclosed. |
| 申请公布号 |
EP2147116(B1) |
申请公布日期 |
2016.03.02 |
| 申请号 |
EP20080746255 |
申请日期 |
2008.04.18 |
| 申请人 |
SIGMA-TAU RARE DISEASE LTD |
发明人 |
FILPULA, DAVID R.;YOUNGSTER, STEPHEN K. |
| 分类号 |
C12N9/78;A61K38/00;A61K47/48 |
主分类号 |
C12N9/78 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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