| 发明名称 |
MMP activated vascular disrupting agents |
| 摘要 |
The present invention relates to compounds, and pharmaceutically acceptable salts thereof, comprising a vascular disrupting agent (VDA) associated and a MMP proteolytic cleavage site. The compounds are useful in the treatment of cancer. |
| 申请公布号 |
EP2481428(B1) |
申请公布日期 |
2016.03.02 |
| 申请号 |
EP20120160556 |
申请日期 |
2008.03.27 |
| 申请人 |
INCANTHERA LIMITED |
发明人 |
GILL, JASON;LOADMAN, PAUL;FALCONER, ROBERT;PATTERSON, LAURENCE;ATKINSON, JENNIFER;BIBBY, MICHAEL |
| 分类号 |
A61K47/48;A61P9/08;A61P29/02;A61P35/00;C07K7/06 |
主分类号 |
A61K47/48 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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