发明名称 |
COMPLEX |
摘要 |
The present invention relates to a covalent complex of von Willebrand Factor (VWF) and Factor VIII, wherein the complex is modified such that it has an extended half-life in vivo. The invention further relates to a method of producing the complex, as well as the therapeutic or prophylactic use of the complex for treating or preventing bleeding events. |
申请公布号 |
EP2988772(A1) |
申请公布日期 |
2016.03.02 |
申请号 |
EP20140722135 |
申请日期 |
2014.04.22 |
申请人 |
CSL LTD. |
发明人 |
METZNER, HUBERT;SCHULTE, STEFAN;WEIMER, THOMAS |
分类号 |
A61K38/37;A61K47/48;A61P7/04;C07K14/755 |
主分类号 |
A61K38/37 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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