Use of oxycodone for treating visceral pain

摘要

It is possible to effectively treat moderate to severe visceral pain by administering analgesic medications comprising the opioid oxycodone or pharmaceutically acceptable salts thereof. Visceral pain and especially acute (i.e. non-chronic) visceral pain can be effectively treated by administering oxycodone at a dosage which is lower than the corresponding dosage of the other opioids like morphine.

主权项

1. A method of treating acute post-operative visceral pain in a human patient, which method comprises:
(a) administering to the patient a unit dosage form comprising oxycodone, or a pharmaceutically acceptable salt thereof, without other active opioid analgesic agents; (b) monitoring one or more pharmacodynamic parameters elicited by said unit dosage form in the patient; (c) adjusting the amount of oxycodone or pharmaceutically acceptable salt thereof in the unit dosage form if the one or more pharmacodynamic parameters are not appropriate for treatment; and (d) administering the unit dosage form containing the adjusted amount of oxycodone or pharmaceutically acceptable salt thereof to the patient; in which steps of monitoring (b), adjusting (c), and administering (d) are repeated until the pharmacodynamic parameters are appropriate for treatment.