发明名称 ウイルス、バクテリア、寄生生物に感染した細胞及び/又は腫瘍細胞に影響を及ぼす生物学的有効分子群、及び該分子群を適用するための方法
摘要 The aim of the invention is to effectively inhibit virus-, bacteria-, or parasite-infected cells and tumor cells in a targeted manner, even in the case of mutations. According to the invention, biologically active molecules are administered, said biologically active molecules including at least one protease inhibitor for at least one specific target protease of the virus-, bacteria-, or parasite-infected cells and/or tumor cells and at least one peptide-inhibited siRNA, PNA or RNA, the peptide bond of which is broken by the at least one target protease for the purpose of activating the peptide-inhibited siRNA, PNA or RNA. The molecules are used, for example, to influence the gene expression of diseased and infected organs or cells.
申请公布号 JP5873808(B2) 申请公布日期 2016.03.01
申请号 JP20120548338 申请日期 2011.01.11
申请人 フリードリヒ−シラー−ユニバーシタット イエナ 发明人 ペールマン,トビアス;グンター,ロルフ
分类号 A61K48/00;A61K31/7088;A61K31/7105;A61K31/713;A61K45/00;A61K47/34;A61K47/36;A61K47/44;A61K47/48;A61P31/04;A61P31/12;A61P33/00;A61P35/00;A61P43/00 主分类号 A61K48/00
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