| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a tablet containing a poorly water-soluble nonsteroidal anti-inflammatory agent satisfying disintegration and elution properties. <P>SOLUTION: The tablet includes (A) the poorly water-soluble nonsteroidal anti-inflammatory agent, (B) sucrose fatty acid ester having a solidifying point of 30°C or higher and an HLB of 9 or larger, (C) a compound selected from light silicic acid anhydride, hydrated silicon dioxide and sodium stearyl fumarate, (D) a compound selected from crystalline cellulose, crystalline cellulose silicide and powder cellulose, and (E) a disintegrant. The content mass ratio represented by (B)/(A) of component (B) to component (A) is 0.03-0.4. <P>COPYRIGHT: (C)2013,JPO&INPIT |
