发明名称 |
IL-15 and IL-15Raplha sushi domain based modulokines |
摘要 |
The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an immunomodulatory antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15Rα or derivatives thereof; and uses thereof. |
申请公布号 |
AU2014304931(A1) |
申请公布日期 |
2016.02.25 |
申请号 |
AU20140304931 |
申请日期 |
2014.08.08 |
申请人 |
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS;UNIVERSITE PARIS DESCARTES;CYTUNE PHARMA |
发明人 |
GEY, ALAIN;TARTOUR, ERIC;BECHARD, DAVID |
分类号 |
C07K14/54;C07K14/715;C07K16/28;C12N15/62 |
主分类号 |
C07K14/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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