Method for Administering Metformin

摘要

A device and method for administering a consistent and steady dosage of Metformin to patients which includes an implantation component with a composition of Metformin adapted to be inserted either subdermally or subcutaneously to administer a steady incremental dosage of Metformin to the patient throughout a predetermined period of time. A Metformin drug suspension is dispersed in a plurality of microreservoirs and the mixture of microreservoirs and placed in a silicone polymer tube for in situ polymerization and molding, which would allow Metformin molecules to initially diffuse through the microreservoir membrane and then through the silicone polymer containing membrane. In a further embodiment, Metformin implants may be formed by dispersing the drug in a copolymer matrix, which is then coated with a copolymer that serves as a rate-controlling membrane. The drug permeation through the polymer membrane occurs at a rate that is slower than that through the polymer matrix.

主权项

1. A method for administrating medication for treating diabetic conditions and pre-diabetic conditions to a patient, comprising:
selecting an implant adapted to be inserted into a patient's body to administer an incremental dosage of the medication to a patient throughout a predetermined period of time; selecting an appropriate dosage of said medication for treating diabetic conditions and pre-diabetic conditions to be contained within said implant whereby said medication for treating diabetic conditions and pre-diabetic conditions is diffused from said implant and absorbed into the patient's bloodstream; and implanting said implant at a selected site on the patient's body.