| 发明名称 |
Genetically modified <i>Babesia </i>parasites expressing protective tick antigens and uses thereof |
| 摘要 |
The present invention relates to methods for stable transfection of Babesia parasites, and for vaccines conferring immunity against parasitic arthropods. |
| 申请公布号 |
US9265818(B2) |
申请公布日期 |
2016.02.23 |
| 申请号 |
US200812114988 |
申请日期 |
2008.05.05 |
| 申请人 |
The United States of America, as represented by the Secretary of Agriculture;Washington State University Research Foundation |
发明人 |
Suarez Carlos E.;Knowles, Jr. Donald P.;McElwain Terry F. |
| 分类号 |
A61K39/018;C12N1/11;A61P33/02;C12N15/63;A61K39/00;C07K14/435 |
主分类号 |
A61K39/018 |
| 代理机构 |
|
代理人 |
Fado John D.;Marks David L.;Shaw Lesley |
| 主权项 |
1. A genetically modified Babesia bovis parasite comprising a stably transfected heterologous nucleic acid, wherein the heterologous nucleic acid comprises a nucleic acid sequence encoding a protective tick antigen selected from the group consisting of the Bm86 of Boophilus microplus, the Bm91 of Boophilus microplus, and the Bm95 of Boophilus microplus. |
| 地址 |
Washington DC US |
